The ability to connect data with analytics is becoming increasing mission critical for 21st century toxicology, with the availability of large-scale data on multiple dimensions. Computational platforms for data aggregation, analysis and visualization
S2. Systems Biology and Toxicology
The pharmacogenetics of ADME genes, receptors, transporters, ion channels and immune response greatly improved an understanding of genetic determinants of adverse drug reactions (ADR). Tangible results with high clinical relevance
Percellome project was initiated in order to reinforce and eventually replace the “safety factor (uncertainty factor)” widely used for the extrapolation of experimental animal data to humans in Toxicology.