The importance of performing drug toxicity screening in the early phase of pharmaceutical development is well known.Currently, human stem cells including iPSC (induced pluripotent stem cells) and iASC (induced Adult Stem Cells) are thought to be useful for the prediction of drug-induced toxicity and for the alternative methods
S4. Stem Cell Bio. and Alt. Testing Methods
Since the establishment of human pluripotent stem cells (hPSC), the capacity of hPSC to differentiate into three germ layer lineages has sparked considerable interest in the regenerative medicine community.
Reprogramming is a process in which a developmentally determined cell fate is re-established to another fate by artificial modifications. Because the genetic information is maintained unchanged after a reprogramming process, the reprogramming technology opens