The importance of performing drug toxicity screening in the early phase of pharmaceutical development is well known. Currently, human stem cells including iPSC (induced pluripotent stem cells) and iASC (induced Adult Stem Cells)
S4. Stem Cell Bio. and Alt. Testing Methods
Metal-based nanoparticles have great application in industries. However, Nanoparticles frequently have remarkably physicochemical properties which will modulate their disposition and toxic potential in biological systems.
Human stem cells including induced pluripotent stem cells and induced adult stem cells are thought to be useful for the prediction of drug-induced toxicity and for the alternative methods substitute of animal testing.
Since the establishment of human pluripotent stem cells (hPSC), the capacity of hPSC to differentiate into three germ layer lineages has sparked considerable interest in the regenerative medicine community.