S5: A Prototype of Eco-PDS: An Eco-friendly Product Design Support Tool for Screening Mixture Toxicity
Korea Institute of Science and Technology
Senior Research Scientist
Chemical industries in the EU have to classify and label mixtures, from 1 June 2015, according to the European regulation on classification, labelling and packaging of substances and mixtures (CLP). Previous related European system on hazard classification and labelling of chemical products, e.g., Directives 67/548/EEC and 1999/45/EC, were replaced by the CLP regulation to be aligned with the United Nations Globally Harmonised System (UN GHS).
Under the CLP, the classification of mixtures can be estimated on the basis of hazard information of mixture itself, similar mixtures, or components in a mixture. Component-based estimation approaches appear to be practically employed for the CLP estimation, due to the lack of toxicity test data on mixtures and chemical combinations.
Accurate and timely CLP estimation is significant; however, the technical guidance document on CLP estimation algorithms for mixtures is complicated, and it requires expert judgement.
This seems to be a burden especially to small and medium-sized enterprises. Therefore, in this study, CLP Mix-Tool, a web-based CLP estimation tool for mixtures was developed as an open software to support chemical industries to effectively comply with the CLP regulation.