OpenTox Euro 2017 Program

Collaboration and integration: Toxicology and risk assessment in the time of dynamic data

TUESDAY, 21 November 2017 (Stucki, Merkur & Mars)

OpenRiskNet Training:

Possible training units offered in the morning or afternoon session depending on interest:  
 
1. Semantic/ontologies: Georgios Gkoutos and Egon Willighagen
2. Biokinetics modelling: Frederic Bois and Ahmed Abdelaziz
3. Workflow management systems (nextflow, squonk): Tim Dudgeon and Cedric Notredame
4. Online modelling with Jaqpot: Philip Doganis (NTUA)
5. QSAR and conformal predictions (CPSign, ModelingWeb): Ola Spjuth
 
11.00 
  OpenTox - OpenRiskNet Training Session 1
13.00
  Lunch 
14.00
 
OpenTox - OpenRiskNet Training Session 2
16.00
 
Coffee Break 
16.30
 
Data Hackathon: Introduction to Case Studies, API Hackathon: Introduction to API concept and current state of implentation in selected software 
17.30
 
Socializing 

Wednesday, 22 November 2017 (Stucki, Saturn 1 & 2) 

08.30
 
Continuation Data and API Hackathons 
11.00
 
Begin OpenTox Euro Conference - Welcome Remarks 
11.15
 S1:
Session 1: Defined approaches towards regulatory acceptance (Co-organized by in3), Chair: Martin Wilks, SCAHT
  1.
Etienne Vermeirssen: In vitro and in vivo bioassays in environmental monitoring
  2. Rex FitzGerald: Test guidelines, AOPs and IATA - current and future
  3.
Paul Jennings: Duck it!
12.45   Lunch 
13.45
S2:
Session 2: Simulations of exposure and transport (Co-organized by SmartNanoTox), Chair: Vladimir Lobaskin, UCD
  1.
Vladimir Lobaskin: The SmartNanoTox project
  2.
Luca Monticelli: Effect of hydrophobic pollutants on biological membranes: a simulation perspective
  3.
Vladimir Lobaskin: Modelling bionano interactions for predictive toxicology
  4.
Giancarlo Franzese: How the Protein Corona Evolves on a Nanoparticle
15.15
 
Coffee Break 
15.30
S3:
Session 3: Characterization of experimental conditions, part 1: nanomaterials (Co-organized by ACEnano),Chair: Iseult Lynch, University of Birmingham
  1.
Iseult Lynch: The ACEnano project and NanoCommons
  2. Andrew Nelson
  3. Iseult Lynch
16.30 
 
OT Development and Activities 
17.15-
 
Poster Session / Social Event 

Thursday, 23 November 2017 (Stucki, Saturn 1 & 2)

08.30
S4: 
Session 4: Integration and interoperability: software (Co-organized by OpenRiskNet), Chair: Chris Evelo (Maastricht University)
  1.
Thomas Exner: The OpenRiskNet project
  2.
Herve Menager: Easing the integration of bioinformatics software and services with the ELIXIR bio.tools registry
  3.
Jildau Bouwman: ENPADASI: Data sharing and integration solutions for nutritional studies
  4.
Alessia Bardi: OpenAIRE services in support of “Open Science as-a-Service”  
10.00   
Coffee Break
10.30 S5: Session 5: Integration and interoperability: data, Chair: Clemens Wittwehr, JRC
  1.
 Johanna McEntyre: ELIXIR Core Data Resources
  2.
Thomas Hill: AOP-driven Predictive Models for Carcinogenicity: an exercise in interoperable data application
  3.
 Thomas Exner: Towards Semantic Interoperability of Publicly Available Data
  4.
Clemens Wittwehr: OECD Harmonised Template 201 – the missing link between AOP science and regulatory acceptance
  5.
Laura Suter-Dick: Liver fibrosis: Corroboration and improvement of the existing AOP using in vitro data
13.00   Lunch 
14.00 S6:
Session 6: High-content imaging (Co-organized by EU ToxRisk), Chair: Bob van der Water, Leiden University
  1. 
Bob van der Water: The EU-ToxRisk project
  2. 
Laura Purdie: Advances in high content imaging in toxicology: 2D and 3D cell based models
  3.
Johannes Delp: Application of high content imaging in screening approaches to detect potentially neurotoxic compounds
  4. 
Bob van der Water: Quantitative high throughput microscopy of adaptive stress responses in chemical safety assessment
15.30  
Coffee Break 
15.45
S7:
Session 7: Characterization of experimental conditions, part 2: cell models, Chair: Iseult Lynch, University of Birmingham
  1.
Paul Jennings: The MSCA-ITN in3 project
  2.
Podium discussion on phenotypic characterization of iPS cell derived models with short introduction to the cell models
17.15   
Final Remarks 
17.30   
Meeting Adjourned