S3: Poster Platform Session

Session 3 Chair: Noffisat Oki

PRESENTING AUTHOR: 
Noffisat Oki
CHAIR PROFILE: 

She is a computational biologist with experience in applying bioinformatics methods, statistical approaches and data mining methods to data analysis and research. Her expertise has been applied to leading and providing support...

SESSION DESCRIPTION: 

This session will kick-off with platform presentations from select post-doctoral trainees working on various aspects of the ToxCast and Tox21 projects. They will be highlighting new and recent developments in the ongoing research in those programs.

S3: Retrofitting an Estrogen Receptor Transactivation Assay with Metabolic Competence Using Alginate Immobilization of Metabolic Enzymes (AIME)

Retrofitting an Estrogen Receptor Transactivation Assay, OpenTox USA 2018
PRESENTING AUTHOR: 
Danica E. DeGroot
ABSTRACT CONTENT / DETAILS: 

The VM7Luc4E2 estrogen receptor (ER) transactivation assay is an OECD approved method (TG 457) for the detection of ER agonists and antagonists, and is also part of the Tox21 high- throughput screening (HTS) portfolio.

S3: Development of QSAR Models for Systemic Toxicity Points of Departure with Variability in Experimental Data

Development of QSAR Models, OpenTox USA 2018
PRESENTING AUTHOR: 
Prachi Pradeep
ABSTRACT CONTENT / DETAILS: 

Human health risk assessment associated with environmental chemical exposure is limited by the tens of thousands of chemicals with little or no experimental in vivo toxicity data. Data gap filling techniques, such as quantitative structure activity relationship (QSAR) models...