In silico modeling

In silico modeling and tools under REACH
Fri, 20. May. 2016

Institute of Life Sciences


Cluj-Napoca, Romania


Prof. Marc Cronin, Liverpool John Moores University (UK)
Dr. Barry Hardy, Douglas Connect GmbH (Switzerland)
Dr. Monica Locatelli, REACH mastery (Italy)

The event is hosted and co-organised by the Romanian Center for Alternative Test Methods (ROCAM)

Organized by Center for Alternatives to Animal Testing (CAAT) a joint venture between University of Konstanz and Johns Hopkins University

REACH EU regulation was adopted to improve the protection of human health and the environment from the risks that can be posed by chemicals, while enhancing the competitiveness of the EU chemicals industry. It also promotes alternative methods for the hazard assessment of substances in order to reduce the number of tests on animals. In this context, this training intends to discuss in depth case studies using in silico tools in order to perform hazard/risk assessment fit for REACH dossiers.

Participants Benefits:

After this 1 day training, the participant will have developed basic knowledges on how to build a read-across case-study as well as becoming more familiar with REACH regulatory requirements and the preparation of a REACH dossier. Moreover, the participant will become more autonomus and will be able to collect specific information from data-rich toxicological databases.

This training targets in particular:

• Risk assessors
• Consultants
• Safety assessors and toxicologists (chemical, cosmetics and drug industry)
• Researchers
• Modellers
• Teachers
• Regulators


08:00-09:00 – Welcome and Registration
09:00-12:00 – Practical session I on QSAR and Read-Across & OpenTox platform
12:00-13:00 – Lunch
13:00-15:00 – Practical session II on COSMOS
15:00-15:30 – Coffee break
15:30-17:30 – Practical session III on IUCLID