Session 2: Adverse Outcome Pathways

OpenTox USA 2015, Session 2: Adverse Outcome Pathways
SESSION 2

Adverse Outcome Pathways
Session Chair: Stephen Edwards, US EPA

Wednesday, 11 February 2015
from 11:00 to 13:00

Speakers Title
Ed Perkins, US Army Engineer R&D Center Development of quantitive AOPs to extrapolate from molecular initiating events to population level Adverse Outcomes
Barry Hardy, Douglas Connect Using OpenTox to map Toxicity Data to AOPs
Dan Villeneuve, US EPA Adverse Outcome Pathways – Principles, Practices, and the Role of Computational Approaches
Lyle Burgoon, US EPA Using Ontologies to Automate Hazard Identification From High Content and High Throughput Screening Assays
Cameron MacKay, Unilever Quantitative Modelling of the AOP for Skin Sensitisation
Session 2 Summary

This session will discuss the development and application of Adverse Outcome Pathways (AOPs) for scientific research and risk assessment purposes. In particular, we will discuss the use of computational tools in supporting AOP development, mapping of evidence to pathway events, and the use of AOPs for environmental risk assessment.

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