Stephen Edwards is a Systems Biologist within the U.S. Environmental Protection Agency’s National Health and Environmental Effects Research Laboratory (EPA-NHEERL) in Research Triangle Park, N.C. Dr. Edwards is the EPA lead for an international effort to develop an Adverse Outcome Pathway (AOP) Knowledgebase, which is designed to house descriptions of the biological mechanisms underlying chemical toxicity in a structured manner.
He is also leading an EPA effort to create computationally-predicted AOPs by integrating data from the published literature, omics databases, and HTS toxicity data. He serves as a senior advisor in the Office of Research and Development (ORD) on issues regarding the development of predictive toxicology models of disease using genomics, proteomics, and metabolomics.
With a combination of experimental and computational experience, Dr. Edwards also serves as a liaison with the EPA’s National Center for Computational Toxicology (NCCT) and has developed a flexible data management system to support systems biology research within the EPA.
Dr. Edwards received his bachelor of science in chemistry from the University of North Carolina at Chapel Hill and his doctorate in pharmacology from Vanderbilt University Medical Center. Before joining the EPA, he served as a senior research scientist and research fellow at Rosetta Inpharmatics (Merck & Co.), in Seattle, Washington, a recognized leader in computational and systems approaches to drug development.