Session 3: Exposure Modelling

OpenTox USA 2015, Session 3: Exposure Modelling
SESSION 3

Exposure Modelling
Session Chair: Tim Pastoor, Syngenta

Wednesday, 11 February 2015
from 14:00 to 16:00

Speakers Title
Michael Dellarco, NICHD/NIH The RISK21 Approach
Daniel A. Vallero, US EPA Exposure Space: Integrating Exposure Data and Modeling with Toxicity Information
Kathie Dionisio, US EPA Data sources for prioritizing human exposure to chemicals
Arpad Szarka, Syngenta Cumulative Exposure
Session 3 Summary

Exposure assessment is too often an afterthought in the risk assessment process. Typically, toxicological information, with its attendant animal testing protocols, drives decision making. Instead, exposure assessment should be a first consideration in formulating a strategy to assess human safety and risk. High exposures to relatively toxic substances should engender different approaches than low exposures to relatively low toxicity substances. HESI's RISK21 approach advocates early problem formulation and tiered exposure and toxicity data development, dependent upon how much precision is necessary to make a safety decision. Depending on the level of detail needed for exposure assessment, various databases and models can be used. This session will explore sources of information for estimating human exposure as well as an array of models that predict human exposure potential.

<< BACK TO PROGRAM << TO SESSION 2 TO SESSION 4 >>