Taverna is an open source and domain-independent Workflow Management System – a suite of tools used to design and execute scientific workflows and aid in silico experimentation" (see http://www.taverna.org.uk/). The latest version natively supports REST web services and users can combine web services to complex workflows.
The goal of this workflow is to upload an SDF file to the OpenTox Ambit dataset service. To build this workflow click "File -> New Workflow", then create a new REST service like in the previous example. This time, however, change the HTTP method to "POST", the URL template to "http://apps.ideaconsult.net:8080/ambit2/dataset" and the 'Accept' header to "text/uri-list".