OpenTox Asia Conference Program
Thursday 24 May
8.45 Introduction and Overview, Barry Hardy (President, OpenTox Association and CEO, Douglas Connect)
Session 1: Systems Toxicology/ Toxicogenomics Chair: Jun Kanno (Japan Bioassay Research Center)
- 8.55 Overview by Chair
- 9.00 Natalia Polouliakh (Sony Computer Science Laboratories, Inc.)
- “Garuda/Shoe and Percellome analytic workflow”
- 9.30 Yayoi Natsume (National Institutes of Biomedical Innovation, Health and Nutrition) “Percellome toxicogenomics data handling by Garuda”
- 10.00 Satoshi Kitajima (National Institutes Health Sciences)
- “Percellome-Project on Sick-Building-Syndrome level inhalation for the prediction of neurobehavioral toxicity”
- 10.30 Coffee break
Session 2: Integrated Testing and Safety Assessment Applications Chair: Chair: Barry Hardy (Douglas Connect, Switzerland)
- 10.55 Overview by Chair
- 11.00 Morihiko Hirota (Shiseido, Japan)
- “Development of an artificial neural network model for risk assessment in skin sensitization using multiple in vitro sensitization tests and in silico parameters”
- 11.30 Anastasios Papadiamantis (University of Birmingham, United Kingdom)
- “Data management in nanosafety research: From bench to database thus streamlining analysis and publication”
- 12.00 Jaeseok Kim (Research Institute of Standards and Science, Republic of Korea)
- “Activities of Center for NanoSafety Metrology in Korea”
- 12.30 Hajime Kojima (National Institute of Health Sciences, Japan)
- ”New trend on alternative to animal testing in Japan”
13.00 - Lunch
Session 3: Integrated Alternative Methods in Predictive Toxicology Chair: Daniele Zink (Agency for Science, Technology and Research, Singapore)
- 14.00 Overview by Chair
- 14.05 Daniele Zink (Agency for Science, Technology and Research, Singapore)
- “How to Build a Predictive In Vitro Method?”
- 14.30 Michael Riediker (Swiss Centre for Occupational and Environmental Health, Switzerland)
- “Predictive toxicology and big data - about the challenge of knowing which dots to connect"
- 15.00 Hao Fan (Agency for Science, Technology and Research, Singapore)
- “Toward an automated computational platform to predict compound binding and toxicity through specific protein targets”
- 15.30 Barry Hardy (Douglas Connect, Switzerland)
- “Collaborative Development of Predictive Toxicology and Safety Assessment Resources - Connecting People and Data for Decision-Making”
15.30 - Coffee break
16.00 - Panel Discussion
17.00 - Poster Session
20.00 - Conference Dinner
Friday 25 May
Session 4: Systems Toxicology Developments supported by Big Data and Artificial Intelligence Chair: Hirokai Kitano (The Systems Biology Institute, Japan)
- 8.55 Chair Remarks
- 9.00 Chun-Wei Tung, PhD (Kaohsiung Medical University, Taiwan)
- “ChemDIS: in silico analysis of chemical-disease association”
- 9.30 Samik Ghosh (The Systems Biology Institute (SBI), Japan)
- “New Horizons in Computational Toxicology”
- 10.00 Prof. Wataru Fujibuchi (Kyoto University, Japan)
- “scChemRISC: A Japanese consortium for sharing chemical risk information assessed by gene networks of human stem cells and machine learning”
10.30 - Coffee break
Session 5: New horizons in toxicology at the intersection of science and technology, Chair: Dr. Samik Ghosh (The Systems Biology Institute (SBI), Japan)
- 10.55 Chair Remarks
- 11.00 Yachie Ayako (The Systems Biology Institute, Japan)
- “Predictive systems toxicology: challenges in mechanistic modeling and structure-based assessment”
- 11.30 Takeshi Hase (Tokyo Medical and Dental University, Japan)
- “DTOX: Deep neural network-based computational framework to analyze omics data in Toxicology”
- 12.00 Vipul Gupta (The Systems Biology Institute, Japan)
- “Garuda: An integrated analytics platform towards toxicity assessment and beyond”
- 12.30 Nick Hird, (Aikomi Corp. Japan)
- “Digital solutions to improve QoL in dementia care”
13.00 - Lunch
14.00 - OpenTox Workshop
16.00 - Panel Discussion
17.00 - Close of Conference