OpenTox Euro 2018 Program
Conference Theme: Bridging the gap between experimental and computational work in safety and risk assessment
Venue: Titania Hotel, Athens, Greece
Dates: October 9-11, 2018
Organising Committee: Barry Hardy (Douglas Connect), Thomas Exner (Douglas Connect), Iseult Lynch ( University of Birmingham), Philip Doganis (NTUA), Thomas Carney (University of Birmingham), Haralambos Sarimveis (NTUA)
Tuesday, 9 October
|
15.30 |
Pre-Conference Hackathon with NanoCommons (link to more information) |
Wednesday, 10 October
|
S1. |
Session 1: Experimental and Computational Toxicological Evaluation of Engineered Nanomaterials, Session Chairs: Costas Charitidis (NTUA) and Vladimir Lobaskin (UCD) |
|
9.00 |
Chair's Introduction |
|
9.10 |
Health and Safety Issues in the development of (nano) carbon-based materials and composites, Kyriaki Kyriakidou (NTUA) |
|
9.40 |
Effect of nanostructured titanium dioxide on photoinduced cancer treatment, Nefeli Lagopati (NTUA) |
|
10.10 |
Multiscale modelling of nanoparticle-membrane interaction, Nick Quirke (Imperial college, UK) |
|
10.40 |
Coffee Break |
|
S2. |
Session 2: Industrial Applications in Safety Assessment, Session Chair: Barry Hardy (Douglas Connect) |
|
11.00 |
Chair Introduction |
|
11.05 |
New Developments in Toxicogenomics Applications, Roland Grafstrom (Karolinska Institute) |
|
11.35 |
Predictive Modelling of Adverse Outcomes, Ola Spjuth (Genetta Soft) |
|
12.05 |
Enalos+ KNIME Nodes for cheminformatics and nanoinformatics applications with the aid of GPU acceleration, Antreas Afantitis (NovaMechanics Ltd) |
|
12.35 |
Collaboration in Integrated Testing and Assessment, Barry Hardy (Douglas Connect) |
|
13.00 |
Lunch |
|
S3. |
Session 3: Hands-on Workshop on Biokinetics Modelling, Led by Haralambos Sarimveis and Philip Doganis (NTUA) |
|
14.00 |
Aim: understanding the use, form, inputs and outputs of physiologically based (PBPK) pharmacokinetic models. Presentation of software applications for developing PBPK models. Customising PBPK to individual time-drug concentration data. Creating optimal drug dosage regimens |
|
16.00 |
Knowledge Café |
|
17.00 |
End of Workday |
|
19.00 |
Dinner in Athens after leaving Titania Hotel |
Thursday, 11 October
|
S4. |
Session 4: Organ-on-a-chip: combining the in-vitro and in-vivo approaches, Session Chair: Andrew Nelson (University of Leeds, UK) |
|
9.00 |
Chair Introduction |
|
9.05 |
Chip-based platform: An in vitro for toxicity screening, Yvonne Kohl, (Fraunhofer IBMT) |
|
9.30 |
Third Generation Rapid High Throughput Screening Platform for Pharma, Toxicants, and Nanomaterials, Andrew Nelson, (University of Leeds, UK) |
| 9.55 | 3D Models and Organs on Chip, Espen Mariussen (Norwegian Institute for Air Research (NILU) |
|
10.30 |
Coffee Break |
|
S5. |
Session 5: In-silico approaches for risk assessment from a regulatory perspective, Session Chair: Andrea Haase (BfR) |
|
11.00 |
Chair Introduction |
|
11.05 |
On the regulatory use of in silico methods under REACH and CLP, Matthias Herzler (BfR) |
|
11.35 |
PBPK based approach towards risk assessment, Barbara Wisniowska (Jagiellonian University) |
|
12.05 |
Towards Nanomaterial Grouping, Andrea Haase (BfR) |
|
12.30 |
Evaluation of the applicability of existing QSAR models and Read Across strategies for predicting the genotoxicity of pesticides and their metabolites, Olga Tcheremenskaia (Istituto Superiore di Sanità) |
|
13.00 |
Lunch |
|
S6. |
Session 6: Hands-on Workshop - Building risk assessment workflows with OpenRiskNet, led by Philip Doganis (NTUA) and Thomas Exner (Douglas Connect) |
|
16.00 |
End of OpenTox Euro 2018 conference |